Ultisil Hilic Silica features a specially treated silica matrix to enhance lifespan and stability when separating strongly polar compounds in high aqueous phases. It operates under multiple retention mechanisms in HILIC mode, offering complementary selectivity to reversed-phase chromatography for unique separation results. The column is optimized for high-volatility mobile phases (>80% organic solvent), making it ideal for mass spectrometry (MS) detection and sensitivity analysis.
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